Article
Tolerance to islet autoantigens in type 1 diabetes.
Annual review of immunology - 1 Jan 2001
Bach J F, Chatenoud L
Abstract excerpt
Tolerance to beta cell autoantigens represents a fragile equilibrium. Autoreactive T cells specific to these autoantigens are present in most normal individuals but are kept under control by a number of peripheral tolerance mechanisms, among which CD4(+) CD25(+) CD62L(+) T cell-mediated regulatio...
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