Article
[Clinical and genetic basis of hypertensive nephrosclerosis. NEFROSEN Study].
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - 1 Jan 2010
Diez Ojea B, Marín R, Coto E, Fernández Vega F, Alvarez Navascués R, Fernández Fresnedo G, Pobes Martínez de Salinas A, Suárez Laurés A, García Monteavaro C, Gorostidi M, Sánchez E, Arias M, Ortega F
Abstract excerpt
BACKGROUND: Hypertensive nephrosclerosis is a chronic kidney disease (CKD) associated with essential hypertension. The lack of correlation between hypertension control and progression to end-stage CKD suggests an intrinsic and primitive disease. New evidence suggests that MYH9 gene alterations are associated with polymorphisms in African Americans. The aim of this study is to investigate whether a polymorphism of...
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