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Congenital-Infantile Fibrosarcoma

1 Mar 2001

Abstract excerpt

Congenital-infantile fibrosarcoma (CIFS) is a relatively indolent sarcoma that should be distinguished from more aggressive spindle cell sarcomas of childhood. CIFSs have been found to have a novel recurrent reciprocal translocation t(12;15)(p13;q25) resulting in the gene fusion ETV6-NTRK3 (ETS variant gene 6; neurotrophic tyrosine kinase receptor type 3). We studied immunohistochemical expression of NTRK3, and...

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PMID: 11242790
DOI: 10.1309/3h24-e7t7-v37g-akkq

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