Article
Use of the Kleihauer test to detect fetal erythroblasts in the maternal circulation.
Prenatal diagnosis - 1 Feb 2001
Martel-Petit V, Petit C, Marchand M, Fleurentin A, Fontaine B, Miton A, Lemarie P, Philippe C, Jonveaux P
Abstract excerpt
Non-invasive prenatal diagnosis of aneuploidies on fetal nucleated erythrocytes present in the maternal circulation is hampered by the extremely small cell number of uncertain origin (70% of erythroblasts circulating during pregnancy have a maternal origin). Therefore, a method allowing selection of the fetal cells among the maternal cells is indispensable after the erythroblast enrichment step. In the present...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.