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Article

Simultaneous fetal cell identification and diagnosis by epsilon-globin chain immunophenotyping and chromosomal fluorescence in situ hybridization

1 Aug 2001

Abstract excerpt

Isolating fetal erythroblasts from maternal blood offers a promising noninvasive alternative for prenatal diagnosis. The current immunoenzymatic methods of identifying fetal cells from background maternal cells postenrichment by labeling gamma-globin are problematic. They are nonspecific because maternal cells may produce gamma-globin, give poor hybridization efficiencies with chromosomal fluorescence in situ...

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Share to Epigenetics and DNA Methylation
Share to Fetal and Pediatric Neurological Disorders
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PMID: 11468149
DOI: 10.1182/blood.v98.3.554

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