Article
Actinin-associated LIM protein-deficient mice maintain normal development and structure of skeletal muscle.
Molecular and cellular biology - 1 Mar 2001
Jo K, Rutten B, Bunn R C, Bredt D S
Abstract excerpt
The actinin-associated LIM protein, ALP, is the prototype of a large family of proteins containing an N-terminal PDZ domain and a C-terminal LIM domain. These PDZ-LIM proteins are components of the muscle cytoskeleton and occur along the Z lines owing to interaction of the PDZ domain with the spectrin-like repeats of alpha-actinin. Because PDZ and LIM domains are typically found in proteins that mediate cellular...
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