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Article

Biased estimation of the recombination fraction using half-sib families and informative offspring.

Genetics - 1 Mar 2001

Gomez-Raya L

Abstract excerpt

A maximum-likelihood method to estimate the recombination fraction and its sampling variance using informative and noninformative half-sib offspring is derived. Estimates of the recombination fraction are biased up to 20 cM when noninformative offspring are discarded. In certain scenarios, the sa...

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Identifiers

PMID: 11238420
DOI: 10.1093/genetics/157.3.1357
PMCID: PMC1461567

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11238420-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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