Methodology and accuracy of estimation of quantitative trait loci parameters in a half-sib design using maximum likelihood.

doi:10.1093/genetics/141.2.755

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Article

Methodology and accuracy of estimation of quantitative trait loci parameters in a half-sib design using maximum likelihood.

Genetics - 1 Oct 1995

Mackinnon M J, Weller J I

Abstract excerpt

Maximum likelihood methods were developed for estimation of the six parameters relating to a marker-linked quantitative trait locus (QTL) segregating in a half-sib design, namely the QTL additive effect, the QTL dominance effect, the population mean, recombination between the marker and the QTL,...

Topics

Alleles
Animals
Confidence Intervals
Crosses, Genetic
Female
Gene Frequency
Genetic Markers
Humans
Male
Mathematics
Models, Genetic
Models, Statistical
Nuclear Family
Probability
Stochastic Processes

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