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Article

Telomerase activity in plasma cell dyscrasias

1 Jan 2001

Abstract excerpt

Activation of telomerase is essential for in vitro cellular immortalization and tumorigenesis. In the present study, we investigated telomerase activation and its implications in plasma cell dyscrasias including monoclonal gammopathy of undetermined significance (MGUS), multiple myeloma (MM) and plasma cell leukaemia (PCL). All 5 patients with MGUS exhibited normal levels of telomerase activity in their plasma...

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PMID: 11237381
DOI: 10.1054/bjoc.2000.1655

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