Article
Effects of propofol vs methohexital on neutrophil function and immune status in critically ill patients.
Journal of anesthesia - 1 Jan 2006
Huettemann Egbert, Jung Annabell, Vogelsang Heinz, Hout Nicole van, Sakka Samir G
Abstract excerpt
PURPOSE: Patients with severe brain injury often require long-term sedation and have a high incidence of nosocomial infections, causing an increased mortality rate. However, whether anesthetic drugs might contribute to immunosuppressive effects remains unclear. METHODS: In this prospective study, we investigated the effects of propofol (4-6 mg x kg(-1) x h(-1)) and methohexital (1-3 mg x kg(-1) x h(-1)) on...
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