Article
Analysis of exonic splicing enhancers in the mouse gonadotropin-releasing hormone (GnRH) gene.
Molecular and cellular endocrinology - 28 Feb 2001
Han J, Seong J Y, Kim K, Wuttke W, Jarry H
Abstract excerpt
We have previously reported that efficient removal of the first intron (intron A) of gonadotropin-releasing hormone (GnRH) pre-mRNA is the prerequisite event for post-transcriptional regulation. In the present study, using an in vitro HeLa splicing system, we examined the enhancing activities of exonic elements for GnRH pre-mRNA splicing. While not excised by exon 2 alone, intron A was efficiently excised when...
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