Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Macrophage tropism of human immunodeficiency virus type 1 facilitates in vivo escape from cytotoxic T-lymphocyte pressure.

Journal of virology - 1 Mar 2001

Schutten M, van Baalen C A, Guillon C, Huisman R C, Boers P H, Sintnicolaas K, Gruters R A, Osterhaus A D

Abstract excerpt

Early after seroconversion, macrophage-tropic human immunodeficiency virus type 1 (HIV-1) variants are predominantly found, even when a mixture of macrophage-tropic and non-macrophage-tropic variants was transmitted. For virus contracted by sexual transmission, this is presently explained by selection at the port of entry, where macrophages are infected and T cells are relatively rare. Here we explore an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Products, rev
Share to Graft vs Host Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Leukocytes, Mononuclear

Share to Macrophages

Share to Mice, Inbred CBA

Share to rev Gene Products, Human Immunodeficiency Virus

Share to T-Lymphocytes, Cytotoxic

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 11222694
DOI: 10.1128/JVI.75.6.2706-2709.2001
PMCID: PMC115895

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Macrophage tropism of human immunodeficiency virus type 1 facilitates in vivo escape from cytotoxic T-lymphocyte pressure.PMID 11222694Read ↗

Macrophages and Cell-Cell Spread of HIV-1Semantic proximity Read ↗

Viral Determinants of HIV-1 Macrophage TropismSemantic proximity Read ↗

Phenotypic Correlates of HIV-1 Macrophage TropismSemantic proximity Read ↗

Generation of Transmitted/Founder HIV-1 Infectious Molecular Clones and Characterization of Their Replication Capacity in CD4 T Lymphocytes and Monocyte-Derived MacrophagesSemantic proximity Read ↗

Complex determinants of macrophage tropism in env of simian immunodeficiency virusSemantic proximity Read ↗

Macrophages in Progressive Human Immunodeficiency Virus/Simian Immunodeficiency Virus InfectionsSemantic proximity Read ↗

Host Restriction Factors Modulating HIV Latency and Replication in MacrophagesSemantic proximity Read ↗

Nef Is Dispensable for Resistance of Simian Immunodeficiency Virus-Infected Macrophages to CD8+ T Cell Killing.Semantic proximity Read ↗

Distinct Effects in Primary Macrophages and Lymphocytes of the Human Immunodeficiency Virus Type 1 Accessory Genes vpr, vpu, and nef: Mutational Analysis of a Primary HIV-1 IsolateSemantic proximity Read ↗

Cellular Compartments of Human Immunodeficiency Virus Type 1 Replication In Vivo: Determination by Presence of Virion-Associated Host Proteins and Impact of Opportunistic InfectionSemantic proximity Read ↗

An infectious molecular clone of an unusual macrophage-tropic and highly cytopathic strain of human immunodeficiency virus type 1Semantic proximity Read ↗

Macrophage tropism determinants of human immunodeficiency virus type 1 in vivoSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.