Article
Spontaneous tandem amplification and deletion of the shiga toxin operon in Shigella dysenteriae 1.
Molecular microbiology - 1 Dec 1999
McDonough M A, Butterton J R
Abstract excerpt
Only one species of Shigella, Shigella dysenteriae 1, has been demonstrated to produce Shiga toxin (Stx). Stx is closely related to the toxins produced by Shiga toxin-producing Escherichia coli (STEC). In STEC, these toxins are often encoded on lambdoid bacteriophages and are major virulence factors for these organisms. Although the bacteriophage-encoded stx genes of STEC are highly mobile, the stx genes in S....
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