Article
penA profile of Neisseria gonorrhoeae in Guangdong, China: Novel penA alleles are related to decreased susceptibility to ceftriaxone or cefixime.
International journal of antimicrobial agents - 1 Apr 2024
Liao Yiwen, Xie Qinghui, Yin Xiaona, Li Xiaoxiao, Xie Junhui, Wu Xingzhong, Tang Sanmei, Liu Mingjing, Zeng Lihong, Pan Yuying, Yang Jianjiang, Feng Zhanqin, Qin Xiaolin, Zheng Heping
Abstract excerpt
BACKGROUND: Resistance to extended-spectrum cephalosporins (ESCs) has become a public health concern with the spread of Neisseria gonorrhoeae and increasing antimicrobial resistance. Mutation of penA, encoding penicillin-binding protein 2, represents a mechanism of ESC resistance. This study sought to assess penA alleles and mutations associated with decreased susceptibility (DS) to ESCs in N. gonorrhoeae....
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