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Article

Threshold effect for teratogenic risk of radiation depends on dose-rate and p53-dependent apoptosis.

International journal of radiation biology - 1 Jan 2001

Kato F, Ootsuyama A, Nomoto S, Kondo S, Norimura T

Abstract excerpt

PURPOSE: To obtain evidence that the p53 gene is indispensable for reduction of high teratogenic risk of radiation at a high dose-rate to zero risk by lowering the dose-rate. MATERIALS AND METHODS: Wild-type p53(+/+), heterozygous p53(+/-) and null p53(-/-) mice were exposed to gamma-rays at high...

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Identifiers

PMID: 11213346
DOI: 10.1080/09553000010001899

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11213346-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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