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Article

The MICA region determines the first modifier locus in familial Mediterranean fever.

Arthritis and rheumatism - 1 Jan 2001

Touitou I, Picot M C, Domingo C, Notarnicola C, Cattan D, Demaille J, Koné-Paut I

Abstract excerpt

OBJECTIVE: Familial Mediterranean fever (FMF) is a genetically recessive inflammatory disease caused by mutations in the MEFV gene. Most patients of non-Ashkenazi Jewish ancestry or those who are homozygous for M694V manifest a severe disease course, but some express a mild form of the disease. W...

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Source

Identifiers

PMID: 11212154
DOI: 10.1002/1529-0131(200101)44:1<163::AID-ANR20>3.0.CO;2-Z

Genes

MICA
MEFV

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11212154-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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The MICA region determines the first modifier locus in familial Mediterranean fever.PMID 11212154Read ↗

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Identification of Disease-Promoting HLA Class I and Protective Class II Modifiers in Japanese Patients with Familial Mediterranean Fever.Semantic proximity Read ↗

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