Article
[In situ PCR in the diagnosis of acute leukemia].
Lijecnicki vjesnik - 1 Jan 2000
Gjadrov Kuvezdić K, Sucić M, Boban D, Marković-Glamocak M, Ries S, Stavljenić-Rukavina A, Labar B
Abstract excerpt
Cytomorphologic and cytochemical bone marrow analysis is essential in the diagnosis of acute leukemia. Immunophenotyping and conventional cytogenetics, just as fluorescent in situ hybridization (FISH) are other diagnostic procedures, as well as genome analysis by PCR (polymerase chain reaction). PCR is inevitable in searching for minimal residual disease, because it may detect very small amount of malignant...
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