Article
[Polymerase chain reaction in diagnostic pathology].
Verhandlungen der Deutschen Gesellschaft fur Pathologie - 1 Jan 1994
Dietel M
Abstract excerpt
DNA is a very stable molecule and fixation as well as routine histological processing does not destroy its molecular structure. Hence the possibility exists to use this material for molecular genetic analyses. The polymerase chain reaction (PCR) opens the chance to amplify DNA to huge amounts from pathological paraffin and plastic blocks and to use this DNA for further examinations, such as detection of mutations...
Topics
- Communicable Diseases
- DNA Primers
- Drug Resistance
- Genotype
- Humans
- In Situ Hybridization
- Lymphoproliferative Disorders
- Neoplasms
- Pathology
- Polymerase Chain Reaction