Article
Special considerations in the evaluation of the hematology and hemostasis of mutant mice.
Veterinary pathology - 1 Jan 2001
Car B D, Eng V M
Abstract excerpt
The study of mutant mice with altered or deficient hematopoietic or hemostatic gene products provides a challenge to the researcher, particularly when genetic alterations lead to lethal phenotypes. The following review provides a framework for understanding murine hematopoiesis, based on work with mutant mice, and details experimental approaches used to evaluate these animals. Mice with deficiencies in hemostatic...
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