Article
Analyses of cutaneous fluoroquinolones photoreactivity using the integrated model for the differentiation of skin reactions.
Journal of photochemistry and photobiology. B, Biology - 1 Oct 2000
Blotz A, Michel L, Moysan A, Blümel J, Dubertret L, Ahr H J, Vohr H W
Abstract excerpt
Currently available test models for the differentiation of photoallergic and photoirritant reactions are extremely time consuming and the protocols are very heterogeneous. In vitro tests are of proven value in predicting irritant or toxic effects, but these tests fail to predict chemical-induced allergic side effects. We developed test systems for this endpoint which is not easily detected by existing assays. In...
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