Article
Beta-thalassemia mutations and haplotype analysis in Lebanon.
Hemoglobin - 1 Nov 2000
Zahed L, Qatanani M, Nabulsi M, Taher A
Abstract excerpt
The molecular basis of beta-thalassemia in Lebanon reflects the heterogeneity of the Lebanese population. Eighteen different mutations were identified among a total of 277 chromosomes. There is evidence of clustering of some mutations in particular geographic regions or among specific religious groups. Haplotype analysis, using seven restriction sites was performed on a total of 110 samples and 11 different...
Topics
- Genetic Linkage
- Haplotypes
- Humans
- Lebanon
- Multigene Family
- Mutation
- beta-Thalassemia