Article
Haplotype analysis of beta thalassemia patients in Western Iran.
Blood cells, molecules & diseases - 1 Jan 2000
Rahimi Zohreh, Muniz Adriana, Akramipour Reza, Tofieghzadeh Fareidon, Mozafari Hadi, Vaisi-Raygani Asad, Parsian Abbas
Abstract excerpt
Beta-thalassemia (beta-thal) is the most common single gene disorder in Iran. To determine the chromosomal background of beta thalassemia mutations in Western Iran we studied beta-globin gene cluster haplotypes in 314 beta-thal and 70 beta(A) chromosomes with a Kurd ethnic background from the province of Kermanshah, Iran using PCR-RFLP. beta-thal mutations were analyzed using PCR-ARMS, RFLP and direct genomic...
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