Article
Molecular characterization of beta-thalassemia in north Jordan.
Hemoglobin - 1 Sept 1994
Sadiq M F, Huisman T H
Abstract excerpt
We have studied the beta-thalassemia mutations in 91 chromosomes of 43 patients with beta-thalassemia major and five with Hb S-beta-thalassemia, aged 6 months to 24 years. Many are blood transfusion-dependent and are being treated at the major hospital, the Princess Basma Hospital, in Irbid, Jordan. As many as 13 different mutations have been identified; three Mediterranean mutations [IVS-I-110 (G-->A), IVS-II-I...
Topics
- Adolescent
- Adult
- Alleles
- Child
- Child, Preschool
- Ethnicity
- Gene Frequency
- Genotype
- Globins
- Humans
- Jordan
- Prevalence
- Sickle Cell Trait