Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tumor necrosis factor-alpha gene polymorphism and death due to acute cellular rejection in a subgroup of heart transplant recipients.

Human immunology - 1 Feb 2001

Azzawi M, Hasleton P S, Turner D M, Yonan N, Deiraniya A K, Sinnott P J, Hutchinson I V

Abstract excerpt

Irreversible acute rejection of the transplanted heart usually has a fatal outcome. Predicting which recipients are most likely to reject might allow closer monitoring and modification of treatment protocols to prevent graft loss. Recipients genetically predisposed to produce more TNF-alpha are those who suffer the most acute rejection episodes. Here we show that TNF-alpha genotype is strongly associated with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Disease
Share to Adjuvants, Immunologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Azathioprine

Share to Cyclosporine

Share to Graft Rejection

Share to Heart Transplantation

Share to Immunosuppressive Agents

Share to Prednisolone

Source

Identifiers

PMID: 11182223
DOI: 10.1016/s0198-8859(00)00235-4

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumor necrosis factor-alpha gene polymorphism and death due to acute cellular rejection in a subgroup of heart transplant recipients.PMID 11182223Read ↗

TNF-alpha in acute cardiac transplant rejection.Semantic proximity Read ↗

Tumor necrosis factor-alpha promoter polymorphisms and the risk of rejection after liver transplantation: a case control analysis of 210 donor-recipient pairs.Semantic proximity Read ↗

Identification of high and low responders to allografts.Semantic proximity Read ↗

Cytokine Gene Polymorphisms and Risks of Acute Rejection and Delayed Graft Function after Kidney TransplantationSemantic proximity Read ↗

Tumour necrosis factor alpha gene polymorphism: a predisposing factor to non-ischaemic myocardial dysfunction?Semantic proximity Read ↗

The Polymorphism -308G/A of Tumor Necrosis Factor-α Gene Modulates the Effect of Immunosuppressive Treatment in First Kidney Transplant Subjects Who Suffer an Acute Rejection.Semantic proximity Read ↗

Cytokine gene polymorphism and heart transplant rejection.Semantic proximity Read ↗

Risk of adverse post-transplant events after kidney allograft transplantation as predicted by CTLA-4 +49 and TNF-alpha -308 single nucleotide polymorphisms: a preliminary study.Semantic proximity Read ↗

The effect of polymorphisms in tumor necrosis factor-alpha, interleukin-10, and transforming growth factor-beta1 genes in acute hepatic allograft rejection.Semantic proximity Read ↗

Interleukin 1 and chronic rejection: possible genetic links in human heart allografts.Semantic proximity Read ↗

Analysis of the polymorphism of the tumour necrosis factor (TNF) gene and promoter and of circulating TNF-alpha levels in heart-transplant patients suffering or not suffering from severe rejection.Semantic proximity Read ↗

Influence of recipient and donor IL-1alpha, IL-4, and TNFalpha genotypes on the incidence of acute renal allograft rejection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.