Article
Axolotl MHC class II beta chain: predominance of one allele and alternative splicing of the beta1 domain.
European journal of immunology - 1 Feb 2001
Laurens V, Chapusot C, del Rosario Ordonez M, Bentrari F, Padros M R, Tournefier A
Abstract excerpt
The axolotl MHC is composed of multiple polymorphic class I loci linked to class II B loci. In this report, evidence of the existence of one class II B locus (Amme-DAB) that codes for two different transcripts is given. A 2.1-kb transcript is translated to a complete beta chain and a shorter transcript of 1.8 kb encodes a molecule lacking the beta1 domain. For two complete class II B mRNA synthesized, up to one...
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