Article
Evidence for balancing selection at the DAB locus in the axolotl, Ambystoma mexicanum.
International journal of immunogenetics - 1 Dec 2007
Richman A D, Herrera G, Reynoso V H, Méndez G, Zambrano L
Abstract excerpt
The axolotl (Ambystoma mexicanum) has been characterized as immunodeficient, and the absence of major histocompatibility complex (MHC) class II polymorphism has been cited as a possible explanation. Here we present evidence for considerable allelic polymorphism at the MHC class II DAB locus for a sample of wild-caught axolotls. Evidence that these sequences are the product of balancing selection for disease...
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