Article
Identification and characterization of estrogen receptor variants in prostate cancer cell lines.
The Journal of steroid biochemistry and molecular biology - 1 Dec 2000
Ye Q, Chung L W, Cinar B, Li S, Zhau H E
Abstract excerpt
A sensitive semi-nested reverse transcriptase-polymerase chain reaction (RT-PCR) amplification was performed to evaluate estrogen receptor-alpha (ER-alpha) mRNA expression in prostate cancer cell lines. We demonstrated the presence of wild-type ER-alpha (wt ER-alpha) and five ER-alpha variants, designated ER-alphaA, B, C, D, and E. Unlike ER-alphaA and D, ER-alphaB, C, and E were not previously reported in normal...
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