Article
Patterns of ancestral human diversity: an analysis of Alu-insertion and restriction-site polymorphisms.
American journal of human genetics - 1 Mar 2001
Watkins W S, Ricker C E, Bamshad M J, Carroll M L, Nguyen S V, Batzer M A, Harpending H C, Rogers A R, Jorde L B
Abstract excerpt
We have analyzed 35 widely distributed, polymorphic Alu loci in 715 individuals from 31 world populations. The average frequency of Alu insertions (the derived state) is lowest in Africa (.42) but is higher and similar in India (.55), Europe (.56), and Asia (.57). A comparison with 30 restriction-site polymorphisms (RSPs) for which the ancestral state has been determined shows that the frequency of derived RSP...
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