Article
Phylogenetics of worldwide human populations as determined by polymorphic Alu insertions.
Electrophoresis - 1 Sept 2002
Antunez-de-Mayolo Gabriela, Antunez-de-Mayolo Adriana, Antunez-de-Mayolo Pamela, Papiha Surinder S, Hammer Michael, Yunis Juan J, Yunis Emilio J, Damodaran Chendi, Martinez de Pancorbo Marian, Caeiro Jose Luis, Puzyrev Valery P, Herrera Rene J
Abstract excerpt
Alu elements, the largest family of interspersed repeats, mobilize throughout the genomes of primates by retroposition. Alu are present in humans in an excess of 500 000 copies per haploid genome. Since some of the insertion alleles have not reached fixation, they remain polymorphic and can be used as biallelic DNA marker systems in investigations of human evolution. In this study, six polymorphic Alu insertional...
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