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Article

Stable expression of human immunodeficiency virus type 1 Nef confers resistance against Fas-mediated apoptosis.

AIDS research and human retroviruses - 20 Jan 2001

Yoon K, Jeong J G, Kim S

Abstract excerpt

To investigate the effect of Nef on Fas-mediated apoptosis, we compared T cells, both population and subclones stably expressing Nef from HIV-1(NL432), with Nef(-) control cells. Fas-mediated apoptosis was significantly delayed in Nef(+) cells as determined by annexin V staining and the percentage of apoptotic cells was lower in all Nef-expressing cells than in the control cells by a maximum of 10-fold. Next we...

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Identifiers

PMID: 11177389
DOI: 10.1089/08892220150217184

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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