Article
Subtype-specific problems with qualitative Amplicor HIV-1 DNA PCR test.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Feb 2001
Bøgh M, Machuca R, Gerstoft J, Pedersen C, Obel N, Kvinesdal B, Nielsen H, Nielsen C
Abstract excerpt
BACKGROUND: commercial HIV-1 qualitative DNA PCR tests have the potential to detect virus in patients in whom antibody tests may be ineffective, such as patients with primary HIV infection and infants born to HIV seropositive mothers. However, the genetic diversity of HIV-1 raises concern about the ability of the PCR tests to detect all current subtypes. OBJECTIVES: to asses the sensitivity of the Amplicor HIV-1...
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