Article
Regulation of invasive cell behavior by taiman, a Drosophila protein related to AIB1, a steroid receptor coactivator amplified in breast cancer.
Cell - 22 Dec 2000
Bai J, Uehara Y, Montell D J
Abstract excerpt
Steroid hormones are key regulators of numerous physiological and developmental processes, including metastasis of breast and ovarian cancer. Here we report the identification of a Drosophila gene, named taiman, which encodes a steroid hormone receptor coactivator related to AIB1. Mutations in tai caused defects in the migration of specific follicle cells, the border cells, in the Drosophila ovary. Mutant cells...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
