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Article

Expression profiles of BRCA1 splice variants in asynchronous and in G1/S synchronized tumor cell lines.

Biochemical and biophysical research communications - 12 Jan 2001

Orban T I, Olah E

Abstract excerpt

Disrupting the function of the BRCA1 gene by mechanisms other than germline mutations is suspected to occur in cases of sporadic breast/ovarian cancers. Using ribonuclease protection assay and multiplex RT-PCR, we examined the change of the total BRCA1 mRNA pool and the expression profile of four predominant BRCA1 splice variants in asynchronous and in G1/S synchronized tumor cell populations compared to normal...

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Identifiers

PMID: 11162473
DOI: 10.1006/bbrc.2000.4068

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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