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Article

The Crithidia fasciculata RNH1 gene encodes both nuclear and mitochondrial isoforms of RNase H.

Nucleic acids research - 1 Feb 2001

Engel M L, Hines J C, Ray D S

Abstract excerpt

The Crithidia fasciculata RNH1 gene encodes an RNase H, an enzyme that specifically degrades the RNA strand of RNA-DNA hybrids. The RNH1 gene is contained within an open reading frame (ORF) predicted to encode a protein of 53.7 kDa. Previous work has shown that RNH1 expresses two proteins: a 38 kDa protein and a 45 kDa protein which is enriched in kinetoplast extracts. Epitope tagging of the C-terminus of the...

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Identifiers

PMID: 11160895
DOI: 10.1093/nar/29.3.725
PMCID: PMC30385

Genes

RNH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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