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Article

Mechanisms Governing Expression of the v-FLIP Gene of Kaposi's Sarcoma-Associated Herpesvirus

15 Feb 2001

Abstract excerpt

Open reading frame 71 (ORF 71) of Kaposi's sarcoma-associated herpesvirus (KSHV) encodes a death effector domain-containing protein that is homologous to cellular FLIPs (FLICE-inhibitory proteins) and is proposed to inhibit Fas-mediated apoptosis. Transcripts bearing ORF 71 (v-FLIP) sequences are present in all latently infected cells. However, mapping studies reveal these to be bi- or tricistronic mRNAs with ORF...

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PMID: 11160684
DOI: 10.1128/jvi.75.4.1857-1863.2001

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Mechanisms Governing Expression of the v-FLIP Gene of Kaposi's Sarcoma-Associated HerpesvirusPMID 11160684Read ↗

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