Article
Plasmid-mediated and inducible cephalosporinase DHA-2 from Klebsiella pneumoniae.
The Journal of antimicrobial chemotherapy - 1 Feb 2001
Fortineau N, Poirel L, Nordmann P
Abstract excerpt
A Klebsiella pneumoniae strain resistant to cefoxitin and oxyimino-cephalosporins was cultured from a child hospitalized in Paris, France, in 1992. This isolate harboured a beta-lactamase gene located on an approximately 200 kb non-self-transferable plasmid. The beta-lactamase identified, DHA-2, shared 99% amino acid identity with the AmpC enzyme of Morganella morganii. DHA-2 was a point-mutant derivative of...
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