Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ubiquitin-based sperm assay for the diagnosis of male factor infertility

1 Feb 2001

Abstract excerpt

Sperm morphology is correlated with fertility in men, yet the existing, subjective sperm morphology assays provide only a limited insight into patients' infertility. Here, we provide the experimental background for a new, objective and automated semen assay, based on the cross-reactivity of defective human spermatozoa with antibodies against a proteolytic marker peptide, ubiquitin. Using immunofluorescence and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function
Share to Urologic and reproductive health conditions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11157815
DOI: 10.1093/humrep/16.2.250

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ubiquitin-based sperm assay for the diagnosis of male factor infertilityPMID 11157815Read ↗

Increased levels of sperm ubiquitin correlate with semen quality in men from an andrology laboratory clinic populationSemantic proximity Read ↗

Sperm ubiquitination positively correlates to normal morphology in human semenSemantic proximity Read ↗

Sperm ubiquitination in patients with dysplasia of the fibrous sheathSemantic proximity Read ↗

Adaptation of ubiquitin-PNA based sperm quality assay for semen evaluation by a conventional flow cytometer and a dedicated platform for flow cytometric semen analysisSemantic proximity Read ↗

Negative biomarker based male fertility evaluation: Sperm phenotypes associated with molecular-level anomalies.Semantic proximity Read ↗

Towards the identification of reliable sperm biomarkers for male infertility: A sperm proteomic approachSemantic proximity Read ↗

Biomarker-based human and animal sperm phenotyping: the good, the bad and the ugly†.Semantic proximity Read ↗

Sumo1-ylation of human spermatozoa and its relationship with semen qualitySemantic proximity Read ↗

The association between mutations in ubiquitin-specific protease 26 (USP26) and male infertility: a systematic review and meta-analysis.Semantic proximity Read ↗

Ubiquitin‐activating enzyme (UBA1) is required for sperm capacitation, acrosomal exocytosis and sperm–egg coat penetration during porcine fertilizationSemantic proximity Read ↗

Protein expression pattern of PAWP in bull spermatozoa is associated with sperm quality and fertility following artificial inseminationSemantic proximity Read ↗

Localization and identification of sumoylated proteins in human sperm: excessive sumoylation is a marker of defective spermatozoaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.