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Article

Increased levels of sperm ubiquitin correlate with semen quality in men from an andrology laboratory clinic population

29 Jan 2004

Abstract excerpt

BACKGROUND: Ubiquitin, a house-keeping protein that marks other proteins for proteasomal degradation, tags defective sperm during epididymal passage. To establish ubiquitin as a biomarker of human infertility, the present study examines the relationships between sperm ubiquitin content and clinical semen parameters among men from an infertility clinic population with varied aetiologies. METHODS: Anti-ubiquitin...

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PMID: 14998962
DOI: 10.1093/humrep/deh131

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