Article
Determination of <i>Helicobacter pylori</i> Virulence by Simple Gene Analysis of the <i>cag</i> Pathogenicity Island
1 Jan 2001
Abstract excerpt
Nucleic acid amplification was performed for five loci in the cag pathogenicity island (PAI) of Helicobacter pylori (comprising cagA, the cagA promoter region, cagE, cagT, and the left end of cagII [LEC]), and gastric inflammation in patients was evaluated. Of 204 H. pylori isolates from Japanese patients (53 with peptic ulcer, 55 with gastric cancer, and 96 with chronic gastritis), 197 (96.6%) were positive for...
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