Regulation of endocytosis by the small GTP-ase rab5.

Article

Regulation of endocytosis by the small GTP-ase rab5.

Cytotechnology - 1 Jan 1993

Zerial M

Abstract excerpt

Rab5 is a small GTPase associated with the plasma membrane and the early endosomes. Expression of wild type rab5 and a mutant protein defective in GTP-binding in BHK cells led to alterations in the rate of endocytosis and in the morphology of endocytic organelles. The results obtained suggest tha...

Topics

Animals
Biotechnology
Cell Line
Cricetinae
Endocytosis
GTP Phosphohydrolases
GTP-Binding Proteins
Membrane Fusion
Mutation
rab5 GTP-Binding Proteins

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