The role of PAX2 in normal and abnormal development of the urinary tract.

doi:10.1007/s004670050533

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Article

The role of PAX2 in normal and abnormal development of the urinary tract.

Pediatric nephrology (Berlin, Germany) - 1 Nov 1998

Eccles M R

Abstract excerpt

The molecular etiology of many urinary tract abnormalities in children remains unknown, but a number of genes with a key role in urogenital development have now been identified. PAX2, one such gene, encodes a transcription factor which is critically required for epithelial differentiation within...

Topics

Animals
DNA-Binding Proteins
Female
Gene Expression Regulation, Developmental
Humans
Kidney
Mice
Mutation
PAX2 Transcription Factor
Pregnancy
Transcription Factors
Urinary Tract

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