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Article

The role of PAX2 in normal and abnormal development of the urinary tract.

Pediatric nephrology (Berlin, Germany) - 1 Nov 1998

Eccles M R

Abstract excerpt

The molecular etiology of many urinary tract abnormalities in children remains unknown, but a number of genes with a key role in urogenital development have now been identified. PAX2, one such gene, encodes a transcription factor which is critically required for epithelial differentiation within the urogenital tract. Recent studies suggest that PAX2 mutations lead to urological abnormalities and renal failure,...

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Source

Identifiers

PMID: 9874314
DOI: 10.1007/s004670050533

Genes

PAX2

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Source receipt: pubmed, retrieved 7 Sept 2026.

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