Article
Lymphocyte P-glycoprotein expression and activity before and after rifampicin in man.
Fundamental & clinical pharmacology - 1 Jan 2000
Becquemont L, Camus M, Eschwege V, Barbu V, Rey E, Funck-Brentano C, Jaillon P
Abstract excerpt
It has recently been shown that P-glycoprotein (P-gp) is inducible by rifampicin in the human gut as shown in intestinal biopsies. The present study was performed in order to test the hypothesis that human peripheral lymphocytes can be used to assess such an inducibility. We also assessed inter- and intra-individual variability of P-gp expression and activity in peripheral lymphocytes. Blood samples from 13...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
