Article
The VP1-unique region of parvovirus B19: amino acid variability and antigenic stability.
The Journal of general virology - 1 Jan 2001
Dorsch Simone, Kaufmann Bärbel, Schaible Uwe, Prohaska Elke, Wolf Hans, Modrow Susanne
Abstract excerpt
The unique region of structural protein VP1 of parvovirus B19 (erythrovirus B19) is important for eliciting neutralizing antibodies that are responsible for eliminating the virus from the peripheral blood and for inducing lifelong immunity. Neutralizing human MAbs bind a conformationally defined epitope spanning VP1 residues 30-42. The DNA sequence encoding the VP1-unique region was determined in parvovirus B19...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
