Article
Four putative subtypes of human parvovirus B19 based on amino acid polymorphism in the C-terminal region of non-structural protein.
Journal of medical virology - 1 Sept 2000
Fukada K, Matumoto K, Takakura F, Yamaki M, Sato H, Okochi K, Maeda Y
Abstract excerpt
The nucleotide sequence of 10 isolates of human parvovirus B19 (B19) were determined and compared throughout 96.3% of the open reading frames (4145 nucleotides from nt. 509-4653). In the 4145 nucleotides, 122 mutation sites were found, of which 24 were accompanied by amino acid displacement. Furthermore, the polymorphism of the amino acids was seen in about 110 bases near the carboxy terminal of the...
Topics
- Amino Acid Sequence
- Amino Acid Substitution
- Base Sequence
- DNA Mutational Analysis
- DNA, Viral
- Genotype
- Humans
- Open Reading Frames
- Parvovirus B19, Human
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Polymorphism, Single-Stranded Conformational
- Viral Nonstructural Proteins