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Article

Association of tumour necrosis factor-alpha, lymphotoxin-alpha and HLA-DRB1 gene polymorphisms with Löfgren's syndrome in Czech patients with sarcoidosis.

Tissue antigens - 1 Feb 2005

Mrazek F, Holla L I, Hutyrova B, Znojil V, Vasku A, Kolek V, Welsh K I, Vacha J, du Bois R M, Petrek M

Abstract excerpt

Sarcoidosis is a granulomatous disorder showing a clear association with MHC (HLA) class I and class II genes. In order to investigate whether polymorphisms of nearby pro-inflammatory genes located within the MHC class III region may also contribute to susceptibility to sarcoidosis or to its clinical manifestation, tumour necrosis factor-alpha (TNF-alpha) and lymphotoxin-alpha (LT-alpha) genes were chosen for...

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Source

Identifiers

PMID: 15713215
DOI: 10.1111/j.1399-0039.2005.00370.x

Genes

TNF
LTA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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