Article
APO E gene and gene-environment effects on plasma lipoprotein-lipid levels.
Physiological genomics - 18 Dec 2000
Hagberg J M, Wilund K R, Ferrell R E
Abstract excerpt
Apolipoprotein E (apo E) is important in plasma lipid metabolism and is a component of several plasma lipoprotein-lipid particles. Three major apo E isoforms are encoded by three common alleles at the APO E locus. The E2 allele is associated with lower and the E4 allele with higher total plasma cholesterol and LDL cholesterol levels compared with the E3 allele. Available data generally indicate that APO E2, and...
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