Article
Apolipoprotein E polymorphisms and concentration in chronic diseases and drug responses.
Clinical chemistry and laboratory medicine - 1 Sept 2000
Siest G, Bertrand P, Herbeth B, Vincent-Viry M, Schiele F, Sass C, Visvikis S
Abstract excerpt
Apolipoprotein (apo) E is an important circulating and tissue protein involved in cholesterol homeostasis and many other functions. The common polymorphism in the coding region of the gene, four polymorphisms in the promoter region, other additional single nucleotide polymorphisms, as well as several apo E variants have been identified. The common coding polymorphism strongly influences the lipid metabolism and...
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