Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Successful Interference with Cellular Immune Responses to Immunogenic Proteins Encoded by Recombinant Viral Vectors

1 Jan 2001

Abstract excerpt

Vectors derived from the adeno-associated virus (AAV) have been successfully used for the long-term expression of therapeutic genes in animal models and patients. One of the major advantages of these vectors is the absence of deleterious immune responses following gene transfer. However, AAV vectors, when used in vaccination studies, can result in efficient humoral and cellular responses against the transgene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to Viral Infectious Diseases and Gene Expression in Insects
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11119597
DOI: 10.1128/jvi.75.1.269-277.2001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Successful Interference with Cellular Immune Responses to Immunogenic Proteins Encoded by Recombinant Viral VectorsPMID 11119597Read ↗

Human Immune Responses to Adeno-Associated Virus (AAV) VectorsSemantic proximity Read ↗

The Complex and Evolving Story of T cell Activation to AAV Vector-encoded Transgene ProductsSemantic proximity Read ↗

Silencing of T lymphocytes by antigen-driven programmed death in recombinant adeno-associated virus vector-mediated gene therapy.Semantic proximity Read ↗

Immune Responses to Muscle-Directed Adeno-Associated Viral Gene Transfer in Clinical StudiesSemantic proximity Read ↗

Immunity and AAV-Mediated Gene Therapy for Muscular Dystrophies in Large Animal Models and Human TrialsSemantic proximity Read ↗

Challenges Posed by Immune Responses to AAV Vectors: Addressing Root CausesSemantic proximity Read ↗

AAV Vectors Vaccines Against Infectious DiseasesSemantic proximity Read ↗

Understanding and Tackling Immune Responses to Adeno-Associated Viral VectorsSemantic proximity Read ↗

Immunogenicity of Recombinant Adeno-Associated Virus (AAV) Vectors for Gene TransferSemantic proximity Read ↗

Impact of AAV Capsid-Specific T-Cell Responses on Design and Outcome of Clinical Gene Transfer Trials with Recombinant Adeno-Associated Viral Vectors: An Evolving ControversySemantic proximity Read ↗

Unraveling the Complex Story of Immune Responses to AAV Vectors Trial After TrialSemantic proximity Read ↗

Humoral Immunity to Adeno-Associated Virus Type 2 Vectors following Administration to Murine and Nonhuman Primate MuscleSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.