Article
Recombinational repair is critical for survival of Escherichia coli exposed to nitric oxide.
Journal of bacteriology - 1 Jan 2001
Spek E J, Wright T L, Stitt M S, Taghizadeh N R, Tannenbaum S R, Marinus M G, Engelward B P
Abstract excerpt
Nitric oxide (NO(.)) is critical to numerous biological processes, including signal transduction and macrophage-mediated immunity. In this study, we have explored the biological effects of NO(.)-induced DNA damage on Escherichia coli. The relative importance of base excision repair, nucleotide excision repair (NER), and recombinational repair in preventing NO(.)-induced toxicity was determined. E. coli strains...
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