Article
Nasopharyngeal angiofibroma: an APC-gene-associated tumor?
Human pathology - 1 Nov 2000
Guertl B, Beham A, Zechner R, Stammberger H, Hoefler G
Abstract excerpt
Nasopharyngeal angiofibromas are extremely rare, locally invasive tumors of unknown cause exclusively occurring in male adolescents. Recently, 6 cases have been reported in patients with familial adenomatous polyposis coli (Gardners syndrome). Mutations or allelic loss of the adenomatous polyposis coli (APC) gene have therefore been implied in the pathogenesis of nasopharyngeal angiofibroma. The authors analyzed...
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